Key result
Long-term residence in a closed community was a risk factor for rotavirus illness, with affected residents having a significantly longer mean duration of stay (22.1 vs 13.5 years; P=0.01).
Why the study?
Does long-term residence in a closed community increase the risk of rotavirus illness among disabled adults?
Observational (n=95)
No
Does long-term residence in a closed community increase the risk of rotavirus illness among disabled adults?
Long-term residence in a closed community may represent a risk factor for rotavirus illness in adults, potentially due to the absence of immuno-stimulation.
Long-term closed-community residence may elevate rotavirus risk in disabled adults; prospective studies needed to confirm association.
An outbreak of group A rotavirus infection resulted in gastroenteritis among disabled adults in an isolated rehabilitation institution in Kobe, Japan. Of the 95 residents, 16 were diagnosed with rotavirus illness. The causative agent was a single strain of typical human group A rotavirus belonging to VP7 serotype G2, VP4 genotype P[4], and NSP4 genotype A. Mean duration of stay was significantly longer for residents with rotavirus illness (22.1+/-11.8 years) than for residents without the disease (13.5+/-10.6 years; P=0.01). Age, sex, disability and location of resident rooms displayed no significant relationships with illness. These observations suggest that long-term residence in a closed community, which might be related to absence of immuno-stimulation, represents a risk factor for rotavirus illness.
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Iijima et al. (2006) conducted an observational in Rotavirus infection (n=95). Long-term residence in a closed community vs. Shorter residence was evaluated on Mean duration of stay for residents with versus without rotavirus illness (p=0.01). Long-term residence in a closed community was a risk factor for rotavirus illness, with affected residents having a significantly longer mean duration of stay (22.1 vs 13.5 years; P=0.01).
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