Population
Adults involved in 3 outbreaks of rotavirus gastroenteritis in the United States
Design
Other
Authors
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G2 predominance in adult outbreaks may signal inadequate heterotypic immunity; leaves open whether strain-targeted vaccines merit development.
The predominance of the G2 rotavirus strain in adult outbreaks suggests that natural immunity to common strains may not provide adequate heterotypic immunity, highlighting a potential target for vaccine development.
Griffin et al. (2002) studied this question.
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