Key result
Vascular risk factors and ultrasonographic and neuroradiologic markers may be useful in the clinical approach to cognitive impairment and risk prediction of Alzheimer's disease.
Cerebrovascular assessment using ultrasonographic and neuroradiologic markers may help predict the risk of Alzheimer's disease and guide treatment strategies in at-risk subjects.
Vascular marker integration may refine cognitive risk assessment; leaves open prospective validation before clinical adoption.
Increasing evidence is emerging that vascular disease and its risk factors play a role in the development of Alzheimer's disease (AD) and affect the probability of an adverse outcome. The aims of this review are to explore the relationship between vascular risk factors and AD and to discuss the potential use of vascular markers in the clinical approach to cognitive impairment. Moreover, we present evidence about the potential use of ultrasonographic and neuroradiologic markers of cognitive impairment in order to establish possible treatment strategies in subjects with a clinical profile at risk of developing AD.
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Silvestrini et al. (2012) conducted a review in Alzheimer's disease and cognitive impairment. Vascular risk factors and markers was evaluated. Vascular risk factors and ultrasonographic and neuroradiologic markers may be useful in the clinical approach to cognitive impairment and risk prediction of Alzheimer's disease.
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