Key result
Systematic microscopic examination of 120 clinically normal thyroids at autopsy revealed incidental lesions mainly in patients over 48, including nodular goiter (26%) and thyroiditis (9%).
Why the study?
What are the incidental histopathological findings in clinically normal thyroid glands at autopsy?
Cross-Sectional (n=120)
What are the incidental histopathological findings in clinically normal thyroid glands at autopsy?
Incidental thyroid lesions, including nodular goiter and microcarcinomas, are common autopsy findings in patients over 48 years old without known thyroid disease.
Common incidental thyroid lesions in older adults should not change practice; leaves open prospective studies on clinical relevance.
Thyroid glands obtained from 120 consecutive autopsies performed on patients who died from different causes, other than thyroid diseases, were systematically examined by light microscopy. There were 84 males and 36 females; their ages ranged from 1 day to 100 years. Histopathological findings were noted mainly in patients older than 48 years of age. In all cases thyroid lesions were incidental findings and included nodular goiter (26%), thyroiditis (9%), follicular adenomas (7%), papillary microcarci nomas (6%), follicular carcinoma (0.8%), and hemangioma (0.8%). A number of other morphologic changes of importance to surgical pathologists were also evaluated such as the presence of solid cell nests, intrathyroidal ectopic tissues, fibrosis, fat cell infiltration, and vascular changes. Int J Surg Pathol 1 (I): 25-32, 1993
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Scopa et al. (1993) conducted a cross-sectional in Clinically normal thyroids (n=120). Systematic examination by light microscopy was evaluated on Incidental thyroid lesions. Systematic microscopic examination of 120 clinically normal thyroids at autopsy revealed incidental lesions mainly in patients over 48, including nodular goiter (26%) and thyroiditis (9%).
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