“Study of C-Reactive Protein, Superoxide Dismutase Level and Biomarkers in Recently Diagnosed Hypertension”

Acute myocardial infarction (AMI) is a significant cause of morbidity and mortality worldwide, which results from occlusion of coronary artery. C-reactive protein (CRP) is an acute phase protein, synthesized by hepatocytes in response to cytokines released into circulation by activated leukocytes. It is a sensitive marker of coronary infl ammation as well as the extent of myocardial necrosis. We incorporated all the ambulant patients (over 18 years old) of both sex having hypertension and normotension going to in the general outpatient office (OPD) for one month. CRP measurement has many advantages in detection and monitoring the acute phase response.This study showed that mean serum CRP levels were increased in the study group. Among two subgroups, mean CRP level increased signifi cantly in the group with risk factors when compared with another group. Most of the male subjects were in 51 – 60 years old and the female were in 41 - 50 years. Among 75 of male subjects, 64% were hypertensive, and among 35females 61% were hypertensive. Mean CRP level in normotensive gathering was 1.072 mg/L (± 0.320) and in hypertensive gathering was 2.824 mg/L (± 0.258). The individuals who created LVH (n=75, 51.02%), their gauge CRP was 2.767 mg/L (±0.318). Key words: Acute myocardial infarction, C-reactive protein, Hypertension, superoxide dismutase.