Key result
Modern antihypertensive drugs generally shift the set-point of the baroreceptor response curve towards lower pressures without causing reflex tachycardia, with some agents restoring reflex sensitivity.
Why the study?
How do different antihypertensive drugs affect baroreceptor reflex control of heart rate and blood pressure in normotensive or hypertensive subjects?
Population
Normotensive or hypertensive subjects
Design
Review
Authors
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May favor modern antihypertensives to avoid reflex tachycardia; leaves open which agents best restore baroreflex sensitivity.
How do different antihypertensive drugs affect baroreceptor reflex control of heart rate and blood pressure in normotensive or hypertensive subjects?
Unlike classical vasodilators, modern antihypertensive agents lower blood pressure without reflex tachycardia by resetting the baroreceptor reflex, with some drugs even restoring its sensitivity.
Berdeaux et al. (1987) conducted a review in Hypertension. Antihypertensive drugs was evaluated. Modern antihypertensive drugs generally shift the set-point of the baroreceptor response curve towards lower pressures without causing reflex tachycardia, with some agents restoring reflex sensitivity.
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