Why the study?
Are plasma catecholamine levels elevated in patients with cerebral infarction or transient ischemic attacks compared to non-stroke controls?
Population
125 patients, including 74 with cerebral infarction, 18 with transient ischemic attacks, and 33 non-stroke…
Design
Case-control
Key result
Cerebral infarction was associated with significantly higher mean plasma norepinephrine levels compared to non-stroke controls (433.2 vs 281.1 pg/ml, p<0.01).
Authors
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Elevated norepinephrine supports sympathetic activation in cerebral infarction; hypothesis-generating for cardiac complications and requires prospective validation.
Observational (n=125)
Are plasma catecholamine levels elevated in patients with cerebral infarction or transient ischemic attacks compared to non-stroke controls?
Absolute Event Rate: 433.2% vs 281.1%
p-value: p=<0.01
Elevated plasma catecholamines in stroke patients suggest increased peripheral sympathetic activity, which may contribute to stroke-related cardiac abnormalities.
Myers et al. (1981) conducted an observational in Cerebral infarction and transient ischemic attacks (n=125). Cerebral infarction vs. Non-stroke controls was evaluated on Mean plasma norepinephrine (pg/ml) (p=<0.01). Cerebral infarction was associated with significantly higher mean plasma norepinephrine levels compared to non-stroke controls (433.2 vs 281.1 pg/ml, p<0.01).
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