Key result
Supine exercise induced significantly higher tension-time index and LV dp/dt at angina onset compared to atrial pacing (P<0.01), while heart rate was greater with pacing (P<0.05).
Why the study?
Does the method of angina induction (supine exercise vs. atrial pacing) alter the hemodynamic responses in patients with severe coronary artery disease?
Population
9 patients with severe coronary artery disease
Comparison
Precipitation of angina by supine exercise vs Precipitation of angina by increasing rates of…
Design
Other
Authors
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Provocation method affects angina hemodynamics; leaves open standardization of ischemia testing in severe CAD.
Observational (n=9)
Does the method of angina induction (supine exercise vs. atrial pacing) alter the hemodynamic responses in patients with severe coronary artery disease?
p-value: p=<0.01
The hemodynamic accompaniments of angina vary significantly depending on the provoking stimulus (exercise vs. pacing), highlighting the complex interrelationships between determinants of myocardial oxygen consumption.
OʼBrien et al. (1969) conducted an observational in severe coronary artery disease (n=9). Supine exercise vs. Atrial pacing was evaluated on Tension-time index and LV dp/dt at the onset of angina (p=<0.01). Supine exercise induced significantly higher tension-time index and LV dp/dt at angina onset compared to atrial pacing (P<0.01), while heart rate was greater with pacing (P<0.05).
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