Key result
Myocardial-specific ablation of Jarid2 in mouse cardiomyocytes leads to dilated cardiomyopathy and impairs neonatal cardiomyocyte maturation.
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Jarid2 ablation induces dilated cardiomyopathy in mice; hypothesis-generating for its role in human cardiomyocyte maturation.
in cardiomyocytes results in DCM and suggest that Jarid2 plays important roles in cardiomyocyte maturation during neonatal stages.
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Cho et al. (2019) studied this question. Myocardial-specific ablation of Jarid2 in mouse cardiomyocytes leads to dilated cardiomyopathy and impairs neonatal cardiomyocyte maturation.
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