Short atrioventricular delay pacing therapy in young and old patients with hypertrophic obstructive cardiomyopathy: good long-term results and a low need for reinterventions

Figure 1. Kaplan–Meier survival curves of cardiac mortality (according to the defined primary endpoints in Methods) from diagnosis in the total cohort of HOCM patients managed. Conservative group (blue), short atrioventricular delay pacing (green), and myectomy (red). N at risk refers to number of patients left in Kaplan–Meier curve. As myectomy group is 25 years younger at the time of diagnosis, the lower attrition rate during early follow-up is to be expected but rapidly increases during later follow-up.

Figure 2. Final results after first intervention (not immediate post-intervention LVOTO gradients, but prior to any reintervention) compared in groups with most similar age profiles, namely conservative medical therapy (n = 121) vs. the total pacing group (n = 88), and pacing <65 years of age (n = 44) with myectomy ≥18 years of age (n = 32). Box-and-whisker plots, with box enclosing two middle quartiles and horizontal line showing the median, whiskers outlining upper and lower quartile values, and with outlier values as dots; conservative (blue), pacing (green), and myectomy (red).