Key result
NCP98 and its associated kinase activity are found predominantly (60-90%) in the soluble fraction of chicken myeloblasts, unlike its viral homolog P140 which is predominantly particulate.
Association with cellular structural components correlates with the transforming activity of proteins containing fps sequences.
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May link fps structural association to transforming activity; leaves open mechanisms in animal myeloblast models.
Young et al. (1984) studied this question. NCP98 vs. P140 was evaluated on Intracellular location (soluble vs particulate fraction). NCP98 and its associated kinase activity are found predominantly (60-90%) in the soluble fraction of chicken myeloblasts, unlike its viral homolog P140 which is predominantly particulate.
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