Key result
Abdominal obesity was not significantly associated with an increased risk of incident CVD after adjusting for metabolic syndrome components and diabetes (HR 1.09; 95% CI 0.98-1.20).
Why the study?
Does abdominal obesity independently increase the risk of incident CHD and stroke compared to metabolic syndrome and diabetes in adults aged ≥45 years?
Population
20,298 men and women aged ≥45 years pooled from the Framingham Offspring, Atherosclerosis Risk in…
Comparison
Abdominal obesity, metabolic syndrome, and… vs Absence of these conditions
Design
Cohort
Follow-up
average 8.3 (s.d. 1.9) years
Authors
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Metabolic syndrome and diabetes should guide CVD risk assessment over abdominal obesity alone; observational data leaves open independent effects in other populations.
Cohort (n=20,298)
Yes
Does abdominal obesity independently increase the risk of incident CHD and stroke compared to metabolic syndrome and diabetes in adults aged ≥45 years?
Hazard Ratio: 1.09 (95% CI 0.98–1.2)
Metabolic syndrome and diabetes are considerably more important prognostic indicators of cardiovascular disease risk than abdominal obesity alone.
Wildman et al. (2010) conducted a cohort in Cardiovascular disease (n=20,298). Abdominal obesity vs. Absence of abdominal obesity was evaluated on Incident coronary heart disease (CHD) and stroke (HR 1.09, 95% CI 0.98-1.20). Abdominal obesity was not significantly associated with an increased risk of incident CVD after adjusting for metabolic syndrome components and diabetes (HR 1.09; 95% CI 0.98-1.20).
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