Key result
This review discusses the diagnosis of depression in older people and reviews the pharmacology and clinical applications of the main antidepressant groups.
Why the study?
What are the pharmacological treatments for depression in older people?
What are the pharmacological treatments for depression in older people?
This review discusses the pharmacological treatment of depression in older people in light of NICE and CSM guidance.
Informs antidepressant selection in older adults per guidelines; leaves open need for updated RCTs.
In the light of recent National Institute for Clinical Excellence (NICE) and Committee for the Safety of Medicines (CSM) guidance we discuss the importance of the diagnosis of depression in old age and review pharmacological interventions. An introductory section is followed by sections on each of the main antidepressant groups. This briefly describes their pharmacology and reviews research done specifically relevant to older people. Finally practical clinical applications are discussed.
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Curran et al. (2006) conducted a review in Depression in older people. Pharmacological interventions (antidepressants) was evaluated. This review discusses the diagnosis of depression in older people and reviews the pharmacology and clinical applications of the main antidepressant groups.
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