Data obtained from a virtually complete ascer-tainment of cases of Huntington's chorea in Queens-land have confirmed that choreics have significantly more offspring than their normal siblings. This is taken as a demonstration of the action of the type of mutation postulated by Medawar (1957) as the explanation of the ageing process; Huntington's chorea thus presents a simplified model which, multiplied and extended, could explain the underlying nature of old age.
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David C. Wallace (1971) studied this question.
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