Key result
Cardiac troponins currently have the highest sensitivity and specificity for myocardial necrosis, representing the biochemical gold standard for diagnosing acute myocardial infarction.
Population
Patients with acute coronary syndrome (ACS) or acute myocardial infarction (AMI)
Design
Review
Authors
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Reinforces troponin as AMI diagnostic standard; confirms consensus yet leaves open novel biomarker validation.
This review summarizes the historical evolution of cardiac biomarkers, highlighting high-sensitivity cardiac troponins as the current gold standard for diagnosing acute myocardial infarction.
Mohan et al. (2017) conducted a review in Acute Coronary Syndrome. Cardiac biomarkers was evaluated. Cardiac troponins currently have the highest sensitivity and specificity for myocardial necrosis, representing the biochemical gold standard for diagnosing acute myocardial infarction.
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