Key result
Sudden cardiac death in the young is frequently caused by inherited cardiomyopathies or channelopathies, highlighting the need for detailed pathological examination and family screening.
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Sudden cardiac death accounts for millions of deaths globally, predominantly driven by ischemic heart disease, highlighting the challenge of identifying asymptomatic at-risk individuals.
Sudden cardiac death is unexpected death within 1 hour of symptoms. A total of 6 million cases of sudden death occur per year world wide with 50 000 in the UK and 300 000–400 000 in the USA (Mazeika, 2001; Anonymous, 2002). Cardiac causes account for 60–80% of cases (Myerburg et al, 1993). Most cases are the result of ischaemic heart disease (Bowker et al, 2003). Detecting those at risk is difficult since many will be asymptomatic and the first presentation may be sudden death.
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Mary N. Sheppard (2010) conducted an editorial in Sudden cardiac death. Sudden cardiac death in the young is frequently caused by inherited cardiomyopathies or channelopathies, highlighting the need for detailed pathological examination and family screening.
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