Ventricular Complexes of the Bundle-Branch-Block Type Associated With Short P-R Intervals

Case Reports1 January 1936VENTRICULAR COMPLEXES OF THE BUNDLE-BRANCH-BLOCK TYPE ASSOCIATED WITH SHORT P-R INTERVALSGEORGE H. ROBERTS, M.D., F.A.C.P., DAVID I. ABRAMSON, M.D.GEORGE H. ROBERTS, M.D., F.A.C.P.Search for more papers by this author, DAVID I. ABRAMSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-7-983 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn recent years a number of electrocardiograms have been reported possessing a shortened P-R interval and a bizarre, widened QRS complex of the type usually associated with an asynchronous activation of the two ventricles. Such cases have been described by Wilson,1 Wedd,2 Hamburger,3 Pezzi,4 Wolff, Parkinson and White,5 Holzmann and Scherf,6 and Wolferth and Wood.7The present report is concerned with an electrocardiographic study of a similar case with some further evidence relevant to the underlying mechanism.CASE REPORTA. N., a male, aged 44 years, a patent attorney by occupation, was seen by one of us in September 1932,...References1. WILSON FN: A case in which the vagus influenced the form of the ventricular complex of the electrocardiogram, Arch. Int. Med., 1915, xvi, 1008-1027. CrossrefGoogle Scholar2. WEDD AM: Paroxysmal tachycardia, Arch. Int. Med., 1921, xxvii, 571-590. CrossrefGoogle Scholar3. HAMBURGER WW: Bundle branch block, Med. Clin. N. Am., 1929, xiii, 343-362. Google Scholar4. PEZZI C: Considérations pathogéniques sur quelques cas de rhythme septal et paraseptal permanents, Arch. d. mal. du coeur, 1931, xxiv, 1-24. Google Scholar5. WOLFFPARKINSONWHITE LJPD: Bundle-branch block with short P-R interval in healthy young people prone to paroxysmal tachycardia, Am. Heart Jr., 1930, v, 685-704. CrossrefGoogle Scholar6. HOLZMANNSCHERF MD: Über Elektrokardiogramme mit verkürzter Vorhof-Kammer-Distanz und positiven P-Zacken, Ztschr. f. klin. Med., 1932, cxxi, 404-423. Google Scholar7. WOLFERTHWOOD CCFC: Mechanism of production of short P-R intervals and prolonged QRS complexes in patients with presumably undamaged hearts, Am. Heart Jr., 1933, viii, 297-311. CrossrefGoogle Scholar8. KENT AF: Observations on the auriculo-ventricular junction of the mammalian heart, Quart. Jr. Exper. Physiol., 1914, vii, 193-195. Google Scholar9. COHNLEVY AR: Experimental studies of the pharmacology of quinidine, Proc. Soc. Exper. Biol. and Med., 1921, xviii, 283-284. CrossrefGoogle Scholar10. LEWIS T: Actions of atropine and quinidine in fibrillation of auricles, Am. Jr. Med. Sci., 1922, clxiv, 1-14. Google Scholar11. SCHOTT E: Zur Frage der Chinidintherapie, Deutsch. Arch. f. klin. Med., 1920, cxxxiv, 208-218. Google Scholar12. WOLFERTH CC: Depression of cardiac conductivity during quinidine therapy, Jr. Am. Med. Assoc., 1923, lxxx, 1289-1291. CrossrefGoogle Scholar13. KORNS HM: Experimental and clinical study of quinidine sulphate, Arch. Int. Med., 1923, xxxi, 15-35; 36-55. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, N. Y.*Received for publication July 18, 1935.From the Department of Physiology and Pharmacology, Long Island College of Medicine, Brooklyn, N. Y. 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