Key result
Early initiation of continuous veno-venous hemodiafiltration for acute renal failure after cardiac surgery reduced hospital mortality compared to conservative usage (23.5% vs 55.5%, p=0.016).
Why the study?
Does early initiation of CVVHDF reduce mortality in adult patients with acute renal failure after cardiac surgery compared to conservative initiation?
Cohort (n=61)
Does early initiation of CVVHDF reduce mortality in adult patients with acute renal failure after cardiac surgery compared to conservative initiation?
Absolute Event Rate: 23.5% vs 55.5%
p-value: p=0.016
Early recognition of acute renal failure and prompt initiation of CVVHDF based on oliguria criteria significantly reduces ICU and hospital mortality in patients after cardiac surgery.
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Supports early CVVHDF in post-cardiac surgery ARF; hypothesis-generating pending RCT confirmation.
Demirkılıç et al. (2004) conducted a cohort in Acute renal failure after cardiac surgery (n=61). Early and intensive use of continuous veno-venous hemodiafiltration (CVVHDF) vs. Conservative usage of CVVHDF was evaluated on Hospital mortality (p=0.016). Early initiation of continuous veno-venous hemodiafiltration for acute renal failure after cardiac surgery reduced hospital mortality compared to conservative usage (23.5% vs 55.5%, p=0.016).
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