January 27, 2017PLoS ONEOpen Access

Quantification of Abdominal Fat in Obese and Healthy Adolescents Using 3 Tesla Magnetic Resonance Imaging and Free Software for Image Analysis

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Why the study?

Does 3T MRI with free software reliably quantify abdominal fat and correlate with cardiometabolic risk markers in obese and healthy adolescents?

Population

57 Caucasian adolescents aged 16-18 years, including 24 overweight/obese and 33 healthy participants…

Design

Cross-sectional

Authors

JEJuliana Cristina EloiPontifícia Universidade Católica do Rio Grande do Sul MEMatias EpifânioHospital Nossa Senhora da Conceição MGMarília Maia de GonçalvesPontifícia Universidade Católica do Rio Grande do Sul

Discussion

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Implication

Waist circumference may surrogate visceral fat and insulin resistance in obese adolescents; leaves open MRI's added value for cardiometabolic risk stratification.

Structured PICO

Does 3T MRI with free software reliably quantify abdominal fat and correlate with cardiometabolic risk markers in obese and healthy adolescents?

Population

57 Caucasian adolescents aged 16-18 years (mean age 16.55 years), including 24 overweight/obese and 33 healthy participants. Exclusion criteria: chronic diseases, hepatorenal disease, and use of hepatotoxic drugs, corticosteroids, or immune suppressants.

Intervention

Abdominal 3 Tesla Magnetic Resonance Imaging (3T MRI) using free software (ImageJ) to quantify visceral and subcutaneous fat.

Outcome

Correlation of visceral and subcutaneous fat area and percentage with anthropometric parameters (waist circumference, BMI, waist-to-height ratio), lipid profile, glucose metabolism, and insulin resistance.surrogate

3T MRI combined with free software provides a radiation-free method to quantify visceral fat, which strongly correlates with waist circumference and markers of insulin resistance in obese adolescents.

Limitations

Only Caucasian adolescents of advanced pubertal stage were included
Did not assess the accuracy of 3T MRI against the gold standard (CT) due to radiation risk

Cite This Study

Eloi et al. (2017) studied this question.

synapsesocial.com/papers/6a2024c4eaa49a33b5fbf5e7 https://doi.org/10.1371/journal.pone.0167625

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Implication

Waist circumference may surrogate visceral fat and insulin resistance in obese adolescents; leaves open MRI's added value for cardiometabolic risk stratification.

Quantification of Abdominal Fat in Obese and Healthy Adolescents Using 3 Tesla Magnetic Resonance Imaging and Free Software for Image Analysis

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Quantification of Abdominal Fat in Obese and Healthy Adolescents Using 3 Tesla Magnetic Resonance Imaging and Free Software for Image Analysis

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

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Also Consider