Key result
Spinal surgery in patients ≥85 linked to ~125% more perioperative complications versus ages 65-74.
Why the study?
Risk factors for perioperative complications and their effect on outcomes in patients aged ≥85 years undergoing spine surgery remain unclear, with lacking comparisons to younger patients.
Does advancing age increase the risk of perioperative complications in older patients undergoing spinal surgery?
Observational (n=132)
No
Does advancing age increase the risk of perioperative complications in older patients undergoing spinal surgery?
Absolute Event Rate: 40.9% vs 18.2%
p-value: p=0.011
Perioperative systemic complications following spinal surgery increase significantly with advancing age, particularly in patients aged ≥85 years, highlighting the need for careful patient selection and multidisciplinary management.
May support cautious selection for spinal surgery in patients ≥85 years; leaves open prospective validation of age thresholds.
STUDY DESIGN: A retrospective comparative study. PURPOSE: To compare the characteristics of perioperative complications in patients aged ≥85 years with those of younger patients undergoing similar spine surgery and examine factors associated with perioperative complications and clinical outcomes among patients aged ≥85 years. OVERVIEW OF LITERATURE: The risk factors for perioperative complications and their effect on outcomes in patients aged ≥85 years remain unclear. Furthermore, no study has compared younger patients with similar surgeries and condition with those aged ≥85 years. METHODS: The study included patients aged ≥65 years who underwent spinal surgeries. The patients aged ≥85, 75-84, and 65-74 years were categorized into the super-old, old, and pre-old groups, respectively. The differences in perioperative age-related complications were compared among the three groups while matching for surgical procedures and general conditions (study 1). Furthermore, preoperative and intraoperative factors were examined for perioperative complications in the super-old group (study 2). Complications were categorized into surgical site and systemic complications. RESULTS: The analysis included 44 patients from each group. In study 1, the total complication rates were 40.9%, 25%, and 18.2% of the super-old, old, and pre-old groups, respectively. Differences in complication rates were observed between the super-old and pre-old groups (p=0.011). In study 2, 58 patients from the super-old group were analyzed. Surgical site complications were significantly associated with longer surgical duration (p=0.02) and more estimated blood loss (p=0.003). Systemic complications were significantly associated with previous cerebrovascular disease (p=0.014), preoperative motor deficit (p=0.023), and emergency case (p=0.006) and negatively associated with diabetes mellitus (p=0.048). CONCLUSIONS: Perioperative complications increased with advancing age in the super-old, old, and pre-old groups. The complication type is associated with specific background factors; therefore, determining them may help prevent perioperative complications.
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Mui et al. (2024) conducted an observational in Spinal degenerative diseases and trauma requiring surgery (n=132). Advanced age (≥85 years) vs. Younger age (65-74 years and 75-84 years) was evaluated on Total perioperative complication rate (p=0.011). Patients aged ≥85 years undergoing spinal surgery had a significantly higher total perioperative complication rate (40.9%) compared to patients aged 65-74 years (18.2%).
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