Key result
Mitral valve repair surgery for degenerative mitral valve regurgitation significantly increased the rate of no or mild regurgitation to 96.6% at 1 month post-operation, with no mortality.
Why the study?
Mitral valve repair is the first priority for degenerative mitral valve regurgitation, motivating an evaluation of its early surgical outcomes.
Does mitral valve repair surgery improve early echocardiographic and clinical outcomes in patients with degenerative mitral valve regurgitation?
Observational (n=59)
No
Does mitral valve repair surgery improve early echocardiographic and clinical outcomes in patients with degenerative mitral valve regurgitation?
Mitral valve repair for degenerative mitral regurgitation demonstrates excellent early safety and efficacy, with 96.6% of patients having no or mild regurgitation at 1 month.
Answers are grounded in this paper and cite their sources.
May support early success of mitral valve repair; hypothesis-generating and requires larger prospective validation.
Background: Mitral valve regurgitation due to degenerative valve disease is a common disease affecting about 2% of the population, mainly in developed countries [2],[6]. Medical treatment only improves symptoms, does not solve the cause of valve regurgitation and does not prevent disease progression, so surgery is the first priority. The surgery of mitral valve repair has a high success rate, low mortality, good long-term result and limiting the risks of implanted valve. Objective: Evaluating the early results of mitral valve repair surgery in the treatment of degenerative mitral valve regurgitation. Material and Methods: Retrospectively, describe a series of mitral valve regurgitation due to degeneration disease in the patients who underwent valve repair operation at Cho Ray hospital from January 2019 to January 2021. Results: From January 2019 to January 2021, 59 patients underwent surgery. The mean age of the study was 53.6 ± 10.6, the male: female ratio 1.56:1. Up to 42.4% of cases received minimally invasive surgery through right thoracotomy. Valve repair techniques are mainly by placing annulus (100%), reducing valve leaflets (50.8%), artificial ligaments (52.5%). The median cardiopulmonary bypass (CPB) time 120 (56-260) minutes, the median aortic clamping time 75 (38-220) minutes, the median mechanical ventilation time 14 (5-180) hours, the median time in resuscitation position 2 (1-6) days. The rate of no/slight regurgitation at1 month after surgery: 96.6%, the average regurgitation was 3.4%. There were no deaths during follow-up, however, there was 1 case requiring re-surgery. Conclusions: Early results after mitral valve repair surgery at Cho Ray hospital gave quite good results. Minimally invasive surgery is increasingly being applied in mitral valve repair operation.
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Tien et al. (2023) conducted an observational in Degenerative mitral valve regurgitation (n=59). Mitral valve repair surgery vs. Pre-operative baseline was evaluated on No or mild mitral regurgitation at 1 month post-surgery (p=<0.001). Mitral valve repair surgery for degenerative mitral valve regurgitation significantly increased the rate of no or mild regurgitation to 96.6% at 1 month post-operation, with no mortality.
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