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Molecular Hybridization of Radioactive Dna to the Dna of Cytological Preparations | Synapse

October 1, 1969Proceedings of the National Academy of Sciences545 citationsOpen Access

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Molecular Hybridization of Radioactive Dna to the Dna of Cytological Preparations

MPMary Lou Pardue JGJoseph G. Gall

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A method is presented for detecting the cellular location of specific DNA fractions. The technique involves the hybridization of a radioactive test DNA in solution to the stationary DNA of a cytological preparation. Sites of DNA binding are then detected by autoradiography. Experiments with DNA of the toad Xenopus are described.

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Pardue et al. (Wed,) studied this question.

synapsesocial.com/papers/6a202710c1b320180d0e0619 https://doi.org/https://doi.org/10.1073/pnas.64.2.600

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