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April 1, 2000The Journal of ImmunologyOpen Access

Neutrophil Tethering on E-Selectin Activates β2 Integrin Binding to ICAM-1 Through a Mitogen-Activated Protein Kinase Signal Transduction Pathway

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Authors

SSScott I. SimonUniversity of California Davis Medical CenterYHYu HuChina North Industries Group Corporation (China)Dietmar VestweberDietmar VestweberUniversity of Bern

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Simon et al. (2000) studied this question.

synapsesocial.com/papers/6a2028bceaa49a33b5fbfd2fhttps://doi.org/10.4049/jimmunol.164.8.4348
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Binding of human peripheral blood polymorphonuclear leukocytes to E-selectin (CD62E) does not promote their activation1997 · 29 citations
  2. 2p38 Mitogen-Activated Protein Kinase Activation Is Required for Human Neutrophil Function Triggered by TNF-α or FMLP Stimulation1998 · 285 citations
  3. 3Requirements for L-selectin in neutrophil-mediated lung injury in rats.1994 · 130 citations
  4. 4L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites.1995 · 445 citations
  5. 5Signal transduction and ligand-receptor dynamics in the neutrophil. Ca2+ modulation and restoration.1985 · 73 citations