The blood supply to most of the human His bundle and its proximal branches is dual in origin, supplied by the A-V node artery and the first septal branch of the left anterior descending artery.
Observational (n=10)
What is the normal blood supply to the human His bundle and proximal bundle branches?
This anatomical study demonstrates that the human His bundle and its proximal branches typically have a dual blood supply from the A-V node artery and the first septal branch of the LAD.
The three major coronary arteries of 10 normal human hearts were injected with differentially colored gelatin mass for histologic determination of the blood supply to the His bundle and proximal bundle branches. The His bundle was dually supplied by the A-V node artery and the first septal branch of the left anterior descending artery in nine hearts, but entirely by the A-V node artery in one. The proximal right bundle branch was supplied by both the A-V node artery and septal branch in five hearts, only the septal branch in four, and the A-V node artery alone in one. The anterior half of the left bundle branch was dually supplied by the A-V node artery and septal branch in four hearts, entirely by the septal branch in five, and the A-V node artery alone in one. The posterior half of the left bundle branch was supplied by the A-V node artery alone in five hearts, dually by the A-V node artery and septal branch in four, and by the septal branch alone in one. The blood supply to most of the human His bundle and its proximal branches is thus dual in origin, with anastomosis principally within the His bundle.
Frink et al. (1973) conducted an observational in Normal human hearts (n=10). Anatomical evaluation of blood supply was evaluated on Blood supply to the His bundle and proximal bundle branches. The blood supply to most of the human His bundle and its proximal branches is dual in origin, supplied by the A-V node artery and the first septal branch of the left anterior descending artery.