July 1, 1982Journal of Biological ChemistryOpen Access

Study of the structure of troponin-I by measuring the relative reactivities of lysines with acetic anhydride.

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Population

Troponin-I protein (free and complexed with troponin-C and troponin-T)

Comparison

Acetylation with [3H]acetic anhydride vs Acetylation with [14C]acetic anhydride in 6 M…

Design

Preclinical

Authors

SGSilvia GregoriIRCCS Ospedale San Raffaele

Discussion

Member takes

Implication

Hypothesis-generating for troponin regulation; leaves open applicability to human cardiac disease.

Structured PICO

Population

Troponin-I protein (free and complexed with troponin-C and troponin-T)

Intervention

Acetylation with [3H]acetic anhydride

Comparator

Acetylation with [14C]acetic anhydride in 6 M guanidine HCl

Outcome

Relative reactivity of lysines in troponin-Isurrogate

The study identifies specific lysine residues involved in the interaction of troponin-I with troponin-C and troponin-T, suggesting that the troponin-IT interaction is modulated by calcium.

Cite This Study

Silvia Gregori (1982) studied this question.

synapsesocial.com/papers/6a202dbe6ed993cb49fbffd4 https://doi.org/10.1016/s0021-9258(18)34387-4

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Study of the structure of troponin-I by measuring the relative reactivities of lysines with acetic anhydride.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Study of the structure of troponin-I by measuring the relative reactivities of lysines with acetic anhydride.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider