Why the study?
Is high pulse pressure associated with higher urine microalbumin levels in Korean adults?
Is high pulse pressure associated with higher urine microalbumin levels in Korean adults?
Higher pulse pressure is significantly associated with elevated urine microalbumin levels, suggesting a link between pulsatile hemodynamics and early renal microvascular damage.
High PP was associated with higher urine microalbumin; hypothesis-generating for pulsatile hemodynamics in early renal damage, needs prospective confirmation.
The aim of this study was to assess the association between microalbumin and pulse pressure (PP) in Korean adults. The study subjects were Korean adults 20 years or older (n=4,948) who participated in the Korea National Health and Nutrition Examination Survey 2012. The urine microalbumin level (MSE) was significantly higher (p=0.047) in the high PP group (PP60.0 mmHg) [33.024.93 g/mL (95% confidence interval (CI), 23.3742.68)] than the normal PP group (PP60.0 mmHg) [22.571.63 g/mL (95% CI, 19.3625.77)], after adjusting for age, gender, smoking, drinking, regular exercising, WM, BMI, TC, TG, HDL-C, FBG, BUN, creatinine, and urine creatinine. In conclusion, pulse pressure was associated with the microalbumin level in Korean adults.
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Gee et al. (2016) studied this question.
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