Key result
Metabolic syndrome increases the risk for cerebrocardiovascular disease and type 2 diabetes, with emerging variables like leptin resistance and aberrant mitochondrial stress adding to its complexity.
Why the study?
The metabolic syndrome is steadily increasing globally, prompting an overview to provide novel insights and propose emerging associated variables beyond its traditional core risk factors.
Design
Overview
Authors
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May inform expanded risk assessment in metabolic syndrome; leaves open validation of emerging mechanisms before clinical adoption.
This review expands the conceptual framework of metabolic syndrome by integrating emerging pathophysiological mechanisms like endothelial dysfunction, oxidative stress, and metainflammation, highlighting new avenues for research.
Melvin R. Hayden (2023) conducted a review in Metabolic syndrome. Metabolic syndrome increases the risk for cerebrocardiovascular disease and type 2 diabetes, with emerging variables like leptin resistance and aberrant mitochondrial stress adding to its complexity.
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