Key result
An 18-month-old girl with noncompaction of the left ventricular myocardium and high factor VIII levels presented with a fatal cardioembolic stroke.
Case Report (n=1)
Highlights the risk of fatal cardioembolic stroke in young children with left ventricular noncompaction, suggesting consideration of prophylactic antithrombotic treatment, especially in the presence of hypercoagulation risk factors.
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Fatal cardioembolic stroke reported in pediatric LV noncompaction with hypercoagulability; leaves open whether antithrombotic prophylaxis improves outcomes.
Noncompaction of myocardium is a rare and recently defined entity that may cause cardioembolism during childhood. We report an 18-month-old girl with noncompaction of the left ventricular myocardium presenting with fatal cardioembolic stroke. The patient had a high factor VIII level, which is known to cause an increased tendency to thromboembolic events. To our knowledge, this is the youngest case with stroke associated with noncompaction of the myocardium. Patients with noncompaction should be considered for prophylactic antithrombotic treatment to prevent mortality and morbidity owing to systemic thromboembolic events, especially if they carry additional risk factors that make them prone to hypercoagulation.
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Hasçelik et al. (2003) conducted a case report in Noncompaction of the left ventricular myocardium (n=1). Noncompaction of the left ventricular myocardium was evaluated on Fatal cardioembolic stroke. An 18-month-old girl with noncompaction of the left ventricular myocardium and high factor VIII levels presented with a fatal cardioembolic stroke.
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