Key result
Cardiac resynchronization therapy improved left ventricular ejection fraction from 30% to 42% and reduced left ventricular end-systolic volume by 20% at 1 year in a patient with repaired tetralogy of Fallot.
Case Report (n=1)
Absolute Event Rate: 42% vs 30%
3D-STE derived activation imaging can effectively visualize interventricular dyssynchrony and guide cardiac resynchronization therapy in patients with complicated adult congenital heart disease.
May support CRT in select repaired tetralogy of Fallot cases; leaves open prospective validation in adult congenital heart disease.
Using 3-dimensional speckle-tracking echocardiography-derived activation imaging system, we visualized interventricular dyssynchrony in a repaired tetralogy of Fallot case with pacing-induced left ventricular dysfunction. The activation imaging system visualized interventricular dyssynchrony and resynchronization after cardiac resynchronization therapy and may be useful to assess electromechanical disturbance in complicated congenital heart diseases. (Level of Difficulty: Intermediate.)
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Ishizu et al. (2020) conducted a case report in Repaired tetralogy of Fallot with pacing-induced left ventricular dysfunction (n=1). Cardiac resynchronization therapy vs. Baseline (pre-CRT) was evaluated on Left ventricular ejection fraction. Cardiac resynchronization therapy improved left ventricular ejection fraction from 30% to 42% and reduced left ventricular end-systolic volume by 20% at 1 year in a patient with repaired tetralogy of Fallot.
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