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A simple label-free method for the detection of Hg(2+) ions with high selectivity and sensitivity has been developed by using fluorescent Au NCs in aqueous media. The sensing mechanism was based on the high-affinity metallophilic Hg(2+)-Au(+) interactions, which effectively quenched the fluorescence of Au NCs.
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Xie et al. (2009) studied this question.
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