Key result
Each 0.1 g/dL increase in pre-operative serum albumin level was associated with a 7.3% decrease in post-operative morbidity and a 15.6% decrease in mortality among colon cancer patients.
Why the study?
Does pre-operative serum albumin level predict post-operative morbidity and mortality in patients with colorectal cancer undergoing elective colectomy?
Population
3732 patients with colon cancer who underwent a potentially curative colectomy
Design
Cohort
Follow-up
post-operative
Authors
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May refine risk stratification in elective colectomy; extends observational data but leaves open whether optimization improves outcomes.
Cohort (n=3,732)
Does pre-operative serum albumin level predict post-operative morbidity and mortality in patients with colorectal cancer undergoing elective colectomy?
p-value: p=<0.001
Pre-operative serum albumin level linearly predicts post-operative morbidity and mortality in colorectal cancer patients, particularly those with hypoalbuminaemia.
Chiang et al. (2015) conducted a cohort in Colon cancer (n=3,732). Pre-operative serum albumin level vs. Lower albumin levels was evaluated on Post-operative morbidity and mortality (p=<0.001). Each 0.1 g/dL increase in pre-operative serum albumin level was associated with a 7.3% decrease in post-operative morbidity and a 15.6% decrease in mortality among colon cancer patients.
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