Why the study?
Does intracoronary fibrinolysis using streptokinase reduce the size of myocardial perfusion defects in patients with acute myocardial infarction?
Population
21 patients with acute myocardial infarction admitted within 4 hours after symptom onset.
Comparison
Intracoronary fibrinolysis using streptokinase. vs Unsuccessful fibrinolysis vs successful…
Design
Cohort
Follow-up
24 hours
Authors
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Successful recanalization associated with reduced perfusion defects in AMI cohort; leaves open whether intracoronary streptokinase improves outcomes in RCTs.
Does intracoronary fibrinolysis using streptokinase reduce the size of myocardial perfusion defects in patients with acute myocardial infarction?
Successful intracoronary fibrinolysis with streptokinase significantly reduces the size of myocardial perfusion defects in acute myocardial infarction, particularly when extensive collaterals or subtotal occlusion are present.
Schüler et al. (1982) studied this question.
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