Why the study?
Does saxagliptin improve renal outcomes in patients with type 2 diabetes?
Does saxagliptin improve renal outcomes in patients with type 2 diabetes?
Saxagliptin improved albuminuria in patients with type 2 diabetes independently of its effect on glycemic control, without affecting eGFR.
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Saxagliptin attenuates albuminuria progression across categories in T2D independent of glycemia; extends RCT evidence for DPP-4i renal effects without eGFR change.
Mosenzon et al. (2016) studied this question.
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