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January 1, 1998Journal of Clinical InvestigationOpen Access

Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release.

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Authors

IGIndira GurubhagavatulaCalifornia University of PennsylvaniaYAYassine AmraniGlenfield HospitalDPDomenico PraticòTemple University

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Cite This Study

Gurubhagavatula et al. (1998) studied this question.

synapsesocial.com/papers/6a204d3f284a522d2e2ed77ehttps://doi.org/10.1172/jci269
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1PECAM-1 is required for transendothelial migration of leukocytes.1993 · 1,159 citations
  2. 2Measurement of cytoplasmic calcium in single microvessels with increased permeability1990 · 59 citations
  3. 3Localization of Multiple Functional Domains on Human PECAM-1 (CD31) by Monoclonal Antibody Epitope Mapping1995 · 65 citations
  4. 4Cylooxygenase-dependent Formation of the Isoprostane, 8-Epi Prostaglandin F2α1995 · 265 citations
  5. 5Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1.1996 · 101 citations