Why the study?
The molecular and cellular mechanisms underlying AF have not been precisely established, prompting interest in how autonomic cardiac regulation initiates and supports AF.
What is the role of the autonomic nervous system in the pathogenesis of atrial fibrillation?
What is the role of the autonomic nervous system in the pathogenesis of atrial fibrillation?
This review highlights the significant role of both sympathetic and vagal autonomic regulation in initiating and sustaining atrial fibrillation.
Autonomic modulation remains investigational in AF; extends mechanistic insights but needs prospective trials before clinical adoption.
The aim of this review was to study the role of the autonomic nervous system in the pathogenesis of atrial fibrillation (AF), as well as to establish the relationship of autonomic regulation with other mechanisms underlying the AF At present, the molecular and cellular mechanisms underlying the AF have not been precisely established. There is interest in evidence showing that both sympathetic outflow and an increased vagal tone can initiate and support AF. As modern studies have shown, autonomic cardiac regulation can be an important factor in the pathogenesis of AF.
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Попова et al. (2020) studied this question.