Key result
Application of 2 compared to 1 freeze-thaw cycles following cryoballoon pulmonary vein isolation did not reduce recurrent atrial fibrillation or tachycardia (46% vs 48%, P=0.84).
Why the study?
Does 2 bonus freeze-thaw cycles compared to 1 bonus cycle reduce recurrent AF or atrial tachycardia in patients with paroxysmal atrial fibrillation undergoing cryoballoon pulmonary vein isolation?
Cohort (n=51)
Does 2 bonus freeze-thaw cycles compared to 1 bonus cycle reduce recurrent AF or atrial tachycardia in patients with paroxysmal atrial fibrillation undergoing cryoballoon pulmonary vein isolation?
Absolute Event Rate: 46% vs 48%
p-value: p=0.84
No takes yet. Share an insight, caveat, or question.
Applying 2 bonus freeze-thaw cycles instead of 1 after cryoballoon PVI does not improve clinical success but increases the risk of phrenic nerve palsy.
Chun et al. (2012) conducted a cohort in Paroxysmal atrial fibrillation (AF) (n=51). 2 bonus freeze-thaw cycles vs. 1 bonus freeze-thaw cycle was evaluated on Recurrent AF or atrial tachycardia (p=0.84). Application of 2 compared to 1 freeze-thaw cycles following cryoballoon pulmonary vein isolation did not reduce recurrent atrial fibrillation or tachycardia (46% vs 48%, P=0.84).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: