Key result
A 31-year-old woman with complex transposition of the great arteries survived without surgery until adulthood and subsequently underwent a successful Jatene operation.
Why the study?
Transposition of the great arteries without surgical correction is fatal during the first year of life, making uncorrected survival to adulthood exceptional.
Case Report (n=1)
This case demonstrates the rare natural survival of a patient with complex transposition of the great arteries to adulthood (31 years) prior to successful corrective surgery.
Answers are grounded in this paper and cite their sources.
May inform counseling on prognosis in unrepaired complex TGA; leaves open optimal timing for late arterial switch.
BACKGROUND: Transposition of the great arteries is the most common cyanotic cardiac lesion in newborns. Transposition of the great arteries without surgical correction is fatal during the first year of life. Contemporary outcome studies have shown that survival rates after surgery are excellent and most patients live to adulthood. CASE SUMMARY: Woman with complex transposition of the great arteries with atrial and ventricular septal defects and subvalvular and valvular pulmonary stenosis, who has survived until the age of 31 years without surgery. The diagnosis was made by echocardiography and cardiac magnetic resonance. She underwent successful corrective surgical treatment after this age, by means of a Jatene operation. CONCLUSION: In transposition of the great arteries patients, a high index of cases dies in the first month of life. Our case represents a natural history of the complex transposition of the great arteries. Non-invasive imaging studies are very useful for the diagnosis and follow-up of patients with transposition of the great arteries, especially echocardiography and cardiac magnetic resonance. In our case, the multimodality approach and the corrective surgery allowed her to survive.
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Narcisse-Alvarez et al. (2019) conducted a case report in Complex transposition of the great arteries with atrial and ventricular septal defects and subvalvular and valvular pulmonary stenosis (n=1). Jatene operation was evaluated on Survival / successful corrective surgical treatment. A 31-year-old woman with complex transposition of the great arteries survived without surgery until adulthood and subsequently underwent a successful Jatene operation.
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