Key result
This review summarizes the physiological background of cardiovascular autonomic dysfunction and the role of laboratory assessment in establishing personalized therapeutic schemes.
Understanding the physiology of the autonomic nervous system and utilizing laboratory assessments are essential for diagnosing and managing cardiovascular autonomic dysfunction.
Laboratory assessment may inform personalized management of cardiovascular autonomic dysfunction; leaves open prospective validation before routine adoption.
Knowledge of the physiology underlying the autonomic nervous system is pivotal for understanding autonomic dysfunction in clinical practice. Autonomic dysfunction may result from primary modifications of the autonomic nervous system or be secondary to a wide range of diseases that cause severe morbidity and mortality. Together with a detailed history and physical examination, laboratory assessment of autonomic function is essential for the analysis of various clinical conditions and the establishment of effective, personalized and precise therapeutic schemes. This review summarizes the main aspects of autonomic medicine that constitute the background of cardiovascular autonomic dysfunction. O conhecimento subjacente à fisiologia do sistema nervoso autónomo é fundamental para se entender a disfunção autonómica na prática clinica. A disfunção autonómica pode resultar primariamente de modificações do sistema ou, secundariamente, a uma série de patologias conducentes a morbilidade ou mortalidade. Juntamente com a colheita detalhada da história clínica e do exame objetivo, a avaliação autonómica laboratorial torna-se essencial na análise de algumas condições clínicas e no estabelecimento de esquemas terapêuticos mais eficazes, refinados e personalizados. Assim, nesta revisão sumarizam-se os aspetos mais relevantes da fisiologia autonómica subjacente a disfunção autonómica cardiovascular.
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Laranjo et al. (2017) conducted a review in Cardiovascular autonomic dysfunction. This review summarizes the physiological background of cardiovascular autonomic dysfunction and the role of laboratory assessment in establishing personalized therapeutic schemes.
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