What question did this study set out to answer?

To compare the long-term prognosis and death rates in treated versus untreated patients with essential hypertension.

January 12, 1969Acta Medica Scandinavica

The Prognosis in Long Term Treated and “Untreated” Essential Hypertension

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Why the study?

Does medical treatment reduce mortality in patients with essential hypertension?

Population

723 patients with essential hypertension, graded according to WHO and Hammarström and Bechgaard's system.

Comparison

Medical treatment for essential hypertension vs An 'untreated' series of hypertensive patients

Design

Cohort

Authors

HMH S MathisenOslo University Hospital HLH. LökenDiakonhjemmet Hospital DBD BroxFriedrich Schiller University Jena

Discussion

Member takes

Implication

Treatment associated with lower mortality in essential hypertension; extends observational data but leaves open RCT confirmation.

Key Points

To compare the long-term prognosis and death rates in treated versus untreated patients with essential hypertension.
Registered 433 patients with essential hypertension since 1955.
Followed up with 290 untreated hypertensive patients for death rate comparison and classification.
Used WHO and Hammarström and Bechgaard's system for grading severity.
Treated men had a death rate of 359% versus an expected 15.61%.
Treated women had a death rate of 228% versus an expected 12.73%.
Untreated men had a death rate of 985% and untreated women 813%, indicating significant mortality reduction with treatment.

Structured PICO

Does medical treatment reduce mortality in patients with essential hypertension?

Population

723 patients with essential hypertension (433 treated [225 men, 208 women] and 290 untreated), graded according to WHO and Hammarström and Bechgaard's system.

Intervention

Medical treatment for essential hypertension

Comparator

An 'untreated' series of hypertensive patients

Outcome

Death rate compared to the corresponding general populationhard clinical

Medical treatment of essential hypertension substantially reduces overall mortality, particularly cerebral deaths in men, compared to untreated patients.

Cite This Study

Mathisen et al. (1969) studied this question.

synapsesocial.com/papers/6a20638ee5585532b8bb5c61 https://doi.org/10.1111/j.0954-6820.1969.tb07331.x

Topics

Hypertension management

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The Prognosis in Long Term Treated and “Untreated” Essential Hypertension

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

The Prognosis in Long Term Treated and “Untreated” Essential Hypertension

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider