What question did this study set out to answer?

To analyze how the accumulation of adverse socioeconomic position throughout life affects the risk of myocardial infarction.

November 15, 2006Journal of Epidemiology & Community HealthOpen Access

Accumulation of adverse socioeconomic position over the entire life course and the risk of myocardial infarction among men and women: results from the Stockholm Heart Epidemiology Program (SHEEP)

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Why the study?

Does the accumulation of adverse socioeconomic position over the life course increase the risk of incident myocardial infarction in men and women?

Key Points

To analyze how the accumulation of adverse socioeconomic position throughout life affects the risk of myocardial infarction.
Case-control study using data from the Stockholm Heart Epidemiology Program.
Included 550 female and 1204 male myocardial infarction patients and matched controls.
Yearly socioeconomic data from birth to disease onset was analyzed to calculate life course adversity.
Relative risk of myocardial infarction for men in adverse socioeconomic position was 2.36 (95% CI 1.79 to 3.11).
Relative risk for women was 2.54 (95% CI 1.70 to 3.78) when always in adverse socioeconomic conditions.
Even a few years in adversity significantly increased myocardial infarction risk, indicating complex selection processes.

Structured PICO

Does the accumulation of adverse socioeconomic position over the life course increase the risk of incident myocardial infarction in men and women?

Population

1,754 patients (550 female, 1204 male) with incident myocardial infarction and 2,315 controls (777 female, 1538 male), comprising Swedish citizens born during 1922-49 and living in Stockholm County during 1992-4.

Intervention

Accumulation of adverse socioeconomic position over the life course (measured as proportion of life spent in manual work)

Comparator

Never having been in adverse socioeconomic position

Outcome

Incident myocardial infarctionhard clinical

Accumulated adverse socioeconomic position over the entire life course significantly increases the risk of incident myocardial infarction in both men and women.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May warrant consideration in MI risk assessment for both sexes; leaves open causal effects and intervention potential from this case-control data.

Cite This Study

Ljung et al. (2006) studied this question.

synapsesocial.com/papers/6a20764e1f3770407f09954e https://doi.org/10.1136/jech.2006.047670

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Implication

May warrant consideration in MI risk assessment for both sexes; leaves open causal effects and intervention potential from this case-control data.

Accumulation of adverse socioeconomic position over the entire life course and the risk of myocardial infarction among men and women: results from the Stockholm Heart Epidemiology Program (SHEEP)

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Accumulation of adverse socioeconomic position over the entire life course and the risk of myocardial infarction among men and women: results from the Stockholm Heart Epidemiology Program (SHEEP)

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider