Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 1, 1983Neurology

A longitudinal study of speech fluency in aphasia

View Full Paper
Ask AI
Bookmark
Share

Authors

David S. KnopmanDavid S. KnopmanKarlsruhe Institute of TechnologyOSOla A. SelnesCross-Cutting CardiologyNNNancy NiccumUniversity of Minnesota

Discussion

Loading...

Member takes

Implication

Longitudinal study assesses speech fluency in stroke-related aphasia, revealing lesion impacts on recovery.

Key Points

  • This research aims to explore the anatomical relationships that influence speech fluency in patients with aphasia caused by stroke.
  • Longitudinal assessment of speech fluency in 54 right-handed patients with aphasia over 5 months.
  • Speech fluency evaluated at 1 month postonset and monthly for 5 months.
  • CT scans obtained at 5 months were used for lesion localization and volume determination.
  • Persistent nonfluency was linked to lesions in the rolandic cortical region and underlying white matter.
  • Recovery from nonfluency was observed in 6 of 27 patients with less extensive lesions than those with persistent nonfluency.
  • Fluent patients at 1 month exhibited no extensive rolandic lesions.

Cite This Study

Knopman et al. (1983) studied this question.

synapsesocial.com/papers/6a20768ccbc595e190317be8https://doi.org/10.1212/wnl.33.9.1170
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Relationship Between Brain Lesions in Patients with Post-Stroke Aphasia and Their Performance in Neuropsychological Language Assessment2025
  2. 2Behavioral Evidence for Continued Language Recovery in Chronic Post-stroke Aphasia (S31.009)2026
  3. 3Beyond the cerebral cortex: cerebellar language-related subregions contributions to fluency in post-stroke aphasia2026
  4. 4Clinical and Linguistic Correlates of Functional Communication Abilities After Stroke: A Longitudinal Study2025
  5. 5Uncovering hidden pathways: structural brain networks under connected speech in post-stroke aphasia2026