Why the study?
Does isradipine prevent an increase in carotid intima-media thickness compared to hydrochlorothiazide in hypertensive patients?
Does isradipine prevent an increase in carotid intima-media thickness compared to hydrochlorothiazide in hypertensive patients?
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Isradipine may offer superior antiatherosclerotic effects compared to hydrochlorothiazide in hypertensive patients, as measured by carotid intima-media thickness, independent of its blood pressure-lowering efficacy.
Hansson et al. (1995) studied this question.
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