Key result
Extracorporeal cardiopulmonary resuscitation successfully supported a 7-year-old female with acute fulminant myocarditis and prolonged cardiac arrest, leading to survival without neurological sequelae.
Why the study?
Does eCPR and VA-ECMO improve survival in pediatric patients with acute fulminant myocarditis and refractory cardiac arrest?
Case Report (n=1)
No
Does eCPR and VA-ECMO improve survival in pediatric patients with acute fulminant myocarditis and refractory cardiac arrest?
eCPR and VA-ECMO can be a successful life-saving bridge therapy with good neurological outcomes in pediatric patients with fulminant myocarditis and prolonged refractory cardiac arrest.
May support eCPR consideration in select pediatric fulminant myocarditis arrests; leaves open broader efficacy.
Fulminant myocarditis is a life-threatening fast progressive condition. We present a 7-year-old female patient admitted with a diagnosis of acute myocarditis with a rapidly progressive cardiac dysfunction despite conventional vasoactive and inotropic treatment. The patient presented with ventricular fibrillation and subsequent cardiac arrest. Cardiopulmonary resuscitation (CPR) was performed during 105 minutes before extracorporeal membrane oxygenation (ECMO) cannulation was performed. Effective hemodynamic function was obtained, and ECMO was weaned after 7 days, without neurological complications. There are not established extracorporeal cardiopulmonary resuscitation (eCPR) treatment criteria, and some international guidelines consider up to 100 minutes of "low flow" phase as a time limit to start the support. Some mortality risk factors for ECMO treatment mortality are female gender, renal failure, and arrhythmias. Pre-ECMO good prognostic factors are high levels of pH and blood lactate.
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Rodriguez-Coronado et al. (2020) conducted a case report in Acute fulminant myocarditis (n=1). Extracorporeal cardiopulmonary resuscitation (eCPR) was evaluated on Survival and neurological outcome. Extracorporeal cardiopulmonary resuscitation successfully supported a 7-year-old female with acute fulminant myocarditis and prolonged cardiac arrest, leading to survival without neurological sequelae.
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