June 20, 2012PLoS ONEOpen Access

Posttraumatic Stress Disorder Prevalence and Risk of Recurrence in Acute Coronary Syndrome Patients: A Meta-analytic Review

View Full Paper

Ask AI

Bookmark

Why the study?

Does ACS-induced PTSD increase the risk of recurrent cardiac events and mortality in patients with acute coronary syndrome?

Population

2,383 patients across 24 observational cohort studies with a history of acute coronary syndrome at least 1…

Comparison

Presence of clinically significant symptoms of… vs Absence of clinically significant symptoms of…

Design

Meta-analysis

Follow-up

mean patient follow-up varied from 1 to 3.5 years

Authors

DEDonald EdmondsonCross-Cutting Cardiology SRSafiya RichardsonNYU Langone Health LFLouise FalzonUniversity of Sheffield

Discussion

Member takes

Implication

May warrant PTSD screening post-ACS; extends meta-analytic support for psychological factors in cardiac prognosis.

Structured PICO

Does ACS-induced PTSD increase the risk of recurrent cardiac events and mortality in patients with acute coronary syndrome?

Population

2,383 patients across 24 observational cohort studies with a history of acute coronary syndrome (myocardial infarction or unstable angina) at least 1 month prior. Mean age varied from 53 to 67 years, 56% to 100% male.

Intervention

Presence of clinically significant symptoms of ACS-induced PTSD (assessed via screening instrument or clinical diagnostic interview)

Comparator

Absence of clinically significant symptoms of ACS-induced PTSD

Outcome

Prevalence of ACS-induced PTSD (across 24 studies) and a composite of adverse clinical outcomes including mortality and/or ACS recurrence/cardiac hospitalization (across 3 studies)composite

ACS-induced PTSD is moderately prevalent (12%) and is associated with a doubled risk of recurrent cardiac events and mortality, highlighting the need for psychological screening and management in post-ACS care.

Limitations

Only studies with relatively small sample sizes have addressed ACS-induced PTSD
Marginally powered to detect associations with outcomes over relatively short intervals
No study to date has been sufficiently powered to test for potential mechanisms or effect modifiers
Did not include unpublished articles or articles from non-peer-reviewed journals
Relied on cruder estimates (e.g., proportion of sample that was male) due to lack of within-group data reporting

Cite This Study

Edmondson et al. (2012) studied this question.

synapsesocial.com/papers/6a207e615654e44f693e86b0 https://doi.org/10.1371/journal.pone.0038915

View Full Paper

Ask AI

Bookmark

Posttraumatic Stress Disorder Prevalence and Risk of Recurrence in Acute Coronary Syndrome Patients: A Meta-analytic Review

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Posttraumatic Stress Disorder Prevalence and Risk of Recurrence in Acute Coronary Syndrome Patients: A Meta-analytic Review

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider