Key result
A proposed model of ventilatory control during exercise suggests that respiratory frequency is primarily regulated by central command, whereas tidal volume is adjusted to meet metabolic requirements.
Why the study?
Understanding of ventilatory control during exercise is limited by challenges in measuring inputs like central command and by overlooking that minute ventilation is the product of differentially regulated respiratory frequency and tidal volume.
This article proposes a new model of ventilatory control during exercise characterized by the differential control and unbalanced interdependence of respiratory frequency and tidal volume.
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May guide interpretation of exercise ventilatory data; leaves open prospective validation of differential frequency and tidal volume control.
Nicolò et al. (2019) conducted a review in Ventilatory control during exercise. Exercise was evaluated. A proposed model of ventilatory control during exercise suggests that respiratory frequency is primarily regulated by central command, whereas tidal volume is adjusted to meet metabolic requirements.
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