Clinical outcomes after the arterial switch operation for transposition. Patient, support, procedural, and institutional risk factors. Congenital Heart Surgeons Society.
Why the study?
What are the clinical outcomes and risk factors for death after the arterial switch operation in neonates with transposition?
Population
513 neonates with simple transposition or transposition and ventricular septal defect entering for diagnosis…
Design
Cohort
Follow-up
5 years
Authors
Discussion
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Member takes
Implication
Highlights need for targeted strategies in high-risk ASO subgroups; extends single-center data but remains hypothesis-generating.
Structured PICO
What are the clinical outcomes and risk factors for death after the arterial switch operation in neonates with transposition?
P
Population
513 neonates with simple transposition or transposition and ventricular septal defect entering for diagnosis and treatment at < 15 days of age
I
Intervention
Arterial switch operation
O
Outcome
Survival at 1 month, 1 year, and 5 years, and risk factors for deathhard clinical
The arterial switch operation provides good early and intermediate-term survival in neonates with transposition, though specific anatomical, procedural, and institutional factors increase mortality risk.
Cite This Study
Kirklin et al. (1992) studied this question.