Respiratory rate predicts outcome after acute myocardial infarction: a prospective cohort study
Key result
Respiratory rate was a significant independent predictor of 5-year total mortality after acute myocardial infarction (HR 1.19 per 1/min; 95% CI 1.12-1.27; P<0.0001).
Why the study?
Does resting respiratory rate predict total mortality in patients after acute myocardial infarction?
Population
941 consecutive patients presenting with acute myocardial infarction, mean age 61 years, 19% female.
Comparison
Measurement of respiratory rate vs Standard clinical assessment
Design
Cohort
Follow-up
5 years
Authors
Discussion
Loading...
Member takes
Implication
Respiratory rate may refine post-MI risk stratification; leaves open prospective validation beyond GRACE and LVEF.
Study Design
Type
Cohort (n=941)
Structured PICO
Does resting respiratory rate predict total mortality in patients after acute myocardial infarction?
P
Population
941 consecutive patients (mean age 61 years, 19% female) presenting with acute MI, followed for 5 years.
E
Exposure
Measurement of respiratory rate (10-min resting recording within 2 weeks after acute MI)
C
Comparator
Standard clinical assessment (including GRACE score, LVEF, and diabetes status)
O
Outcome
Total mortality during a follow-up period of 5 yearshard clinical
Main Result
Hazard Ratio: 1.19 (95% CI 1.12–1.27)
p-value: p=< 0.0001
Resting respiratory rate measured within 2 weeks of an acute MI is a powerful, independent predictor of 5-year mortality, complementary to established risk markers like the GRACE score and LVEF.
Cite This Study
Barthel et al. (2012) conducted a cohort in acute myocardial infarction (n=941). Respiratory rate was evaluated on total mortality (HR 1.19, 95% CI 1.12-1.27, p=< 0.0001). Respiratory rate was a significant independent predictor of 5-year total mortality after acute myocardial infarction (HR 1.19 per 1/min; 95% CI 1.12-1.27; P<0.0001).