Why the study?
What is the effect of heart rate and intracoronary isoproterenol, levarterenol, and epinephrine on coronary flow and resistance?
What is the effect of heart rate and intracoronary isoproterenol, levarterenol, and epinephrine on coronary flow and resistance?
Intracoronary isoproterenol, levarterenol, and epinephrine decrease total coronary resistance primarily through intravascular effects, with negligible impact on extravascular resistance.
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Animal data suggest intravascular dominance in coronary resistance reduction; hypothesis-generating for human coronary flow studies.
Lewis et al. (1961) studied this question.
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