Key result
Myogenic regulatory factors (Myf5, MyoD, Myogenin, and MRF4) are essential transcription factors that orchestrate prenatal and postnatal myogenesis through complex regulatory networks.
Design
Review
Authors
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May guide skeletal muscle regeneration strategies; leaves open translation to cardiac myogenesis.
This review summarizes 30 years of research on myogenic regulatory factors, highlighting their critical roles and regulatory mechanisms in skeletal muscle formation and regeneration.
Asfour et al. (2018) conducted a review in Myogenesis. Myogenic regulatory factors was evaluated. Myogenic regulatory factors (Myf5, MyoD, Myogenin, and MRF4) are essential transcription factors that orchestrate prenatal and postnatal myogenesis through complex regulatory networks.
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