Key result
Myocardial fiber distribution has a direct relation with left ventricular myocardium magnitude of circumferential strain and twist angle in adult rats.
Why the study?
Does myocardial fiber distribution relate to LV circumferential strain and twist angle in adult rats?
Does myocardial fiber distribution relate to LV circumferential strain and twist angle in adult rats?
Myocardial fiber distribution directly correlates with LV circumferential strain and twist angle in adult rats, providing insights into fundamental cardiac mechanics.
No immediate clinical implications; leaves open translation of rat myocardial mechanics to humans.
Left ventricular structure has proved to be related with cardiac function; however the relation of myocardial fiber distribution with regional wall motion remains to be elucidated. In this study, both in vivo tagging and ex vivo DTI studies were performed in adult rats. LV circumferential strain, myocardium twist and myocardial fiber architecture were investigated. Results show that myocardial fiber distribution has direct relation with LV myocardium magnitude of circumferential strain and twist angle. Such integrated functional and structural analysis may provide more information for understanding the fundamental cardiac mechanics and assessment of pathological changes.
No takes yet. Share an insight, caveat, or question.
Wu et al. (2009) studied this question. Myocardial fiber architecture assessment via MR was evaluated on Relation of myocardial fiber distribution with regional wall motion (LV circumferential strain and twist angle). Myocardial fiber distribution has a direct relation with left ventricular myocardium magnitude of circumferential strain and twist angle in adult rats.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: